Studies on Quinolizine Derivatives. X. Synthesis of Cyclazine Derivatives and Their Reactions. (3)

Synthesis of Phosphorus Derivatives via Multicomponent Reactions

Stable derivatives of oxaphosphaphenanthrenes were prepared using multicomponent reactions of 3-bromo-2-naphthol, dialkyl acetylenedicarboxylate and trimethyl or triphenyl phosphite under microwave conditions with good yields. 

Design, synthesis and anti-HIV integrase evaluation of 4-oxo-4H-quinolizine-3-carboxylic acid derivatives.

4-Oxo-4H-quinolizine-3-carboxylic acid derivatives bearing sulfamido, carboxylamido, benzimidazole and benzothiazole substituents have been designed and synthesized. The structures of these new compounds were confirmed by (1)H-NMR, (13)C- NMR, IR and ESI (or HRMS) spectra. Compounds were screened for possible HIV integrase inhibitory activity.

Synthesis and Reactions of Triptycenes and Their Derivatives

In order to verify if the triptycyl (the analog of triphenylmethyl in which the three phenyl groups were united to a CH) free radical 1a (Fig. 2.1) should be more instable than the triphenylmethyl radical itself, Bartlett et al. [1] first synthesized triptycene 1 in a low total yield by a multistep route starting from the Diels–Alder addition reaction of anthracene and benzoquinone (Scheme 2.1)...

Synthesis and characterization of carbazole derivatives and their antimicrobial studies.

The reaction of 1-oxo-1,2,3,4-tetrahydrocarbazoles (1a-e) with paraformaldehyde and ethylenediamine yielded N,N'-bis(1,2,3,4-tetrahydrocarbazol-1-ylidene)ethane-1,2-diamines (2a-e). Here, like in another similar attempt of replacing ethylenediamine by ethanolamine, ended up in formation of 2-{[1-(2-(2-aminoethoxy)ethylimino)-1,2,3,4-tetrahydrocarbazol-2-yl-methyl]amino}ethanols (3a-e). These pr...

synthesis of phosphorus derivatives via multicomponent reactions